MyBioSource.com's COPG2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
Description: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Subunit Structure: Oligomeric complex. Binds to CDC42. Interacts with JAGN1.
Similarity: Belongs to the COPG family